Our mission

To increase access to diagnostics in lower income and lower-middle-income countries (LIC’s and LMIC’s) through affordable innovative technology and sustainable local production.

Problem

There is an urgent need for the differentiation of malaria from other febrile illnesses. The syndrome of fever is the most common presenting complaint among persons seeking healthcare in many low and middle-income countries.  Because of the lack of specificity of existing tests fever patients are often presumptively treated for malaria. These are expensive treatments that take up a significant part of the health care budgets in many African nations.  Additionally, such erroneous presumptive diagnosis leads to over treatment, extends the duration of other undiagnosed illnesses in the patient’s body, and increases the risk of the development of drug resistance.

Production of diagnostic tests are also not affordable and  affordable tests  

Discovery

Several kinds of diagnostic technologies already exist that could be and are in use in resource-limited settings. It’s our belief that lateral flow immuno-assays are best suited for such environments. Prototype test development will be based on this model. We will be making a few simple but innovative modifications that should depress the cost of materials and reagents and improve the versatility of the test in a unique way. Conventional lateral flow assays utilize antibodies as molecular probes/biosensors. We would be replacing these with aptamers.

We have harnessed significant manufacturing cost-saving  benefits with the use of just two recent innovative modifications to traditional fever diagnostic test strips . The modifications also improve test performance/accuracy and increase shelf-life of the finished product across a much broader range of temperatures.

Collaboration

The successful and timely implementation of this project would be dependent on establishing partnerships with key stakeholders involved in policy, research, healthcare delivery, as well as an influential political champion who is closely aligned with our goals and objectives. They would advise us on networking, strategy and ideas for new product development.

Solutions

We believe in using an integrated approach to solving this problem combining the best-suited technology and a customized manufacturing plan reflecting the socio-economic environment. Our solution will help circumvent the impediments created by current traditional market-led business models and also fulfill the ASSURED criteria for point of care tests for infectious disease.

Better treatments through improved diagnostics

Our primary focus is the development and manufacture of a multiplex rapid diagnostic test that would discriminate the origin of fever between parasitic (malaria), viral and bacterial pathogens. Our envisioned prototype comprises of several innovative features and technologies that would make our tests superior to current industry models and also cheaper in cost for the end user.